Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204474 | 0.84 | ALDH1A1 (0.56) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL18860300 | 0.83 | PTPN1 (0.59) | MAPTALDH1A1HDAC1SRD5A2L3MBTL1 | |
| SCHEMBL450084 | 0.79 | RAB9A (0.85) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17148448 | 0.79 | KMT2A (0.52) | MAPTRAB9AALDH1A1LMNAMAPK1 | |
| SCHEMBL7079689 | 0.79 | RAB9A (0.66) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8536624 | 0.79 | ALDH1A1 (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL14739209 | 0.79 | ALDH1A1 (0.55) | MAPTNPC1RAB9AALDH1A1LMNA | |
| SCHEMBL4876093 | 0.79 | MLYCD (0.61) | LMNAMAPK1NPSR1HTTGAA | |
| SCHEMBL11900206 | 0.78 | TDP1 (0.53) | MAPTALDH1A1LMNAMAPK1TDP1 | |
| SCHEMBL507140 | 0.78 | GSK3B (0.57) | MAPTNPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151702-A2 | Alpha-hydroxyketone acetals | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1985-08-21 | — | — | EP | disclosed |
| EP-0048136-A2 | Process for preparing alpha-aromatic group substituted alkanoic acids or esters thereof | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1982-03-24 | — | — | EP | disclosed |