Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29270113 | 0.79 | HDAC3 (0.58) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL11014128 | 0.79 | MAPT (0.58) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL2634592 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL2633915 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL2633940 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL5789171 | 0.75 | ALDH1A1 (0.62) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL11204474 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL3823835 | 0.74 | RAB9A (0.52) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL29041229 | 0.74 | MAPT (0.65) | ALDH1A1LMNARECQLHSD17B10ALOX15 | |
| SCHEMBL29041227 | 0.74 | KMT2A (0.77) | ALDH1A1LMNARECQLHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059924-A1 | PHOTOSTABILISERS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059924-A1 | PHOTOSTABILISERS | ALDH1A1, ALDH18A1, ALDH1A2 | ALDH1A1 1/4885LMNA 3093/4885RECQL 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.