Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017309 | 0.92 | AMY1A (0.40) | AMY1AMAPK10PKN1PKN2RHEB | |
| SCHEMBL11019293 | 0.85 | AMY1A (0.49) | AMY1AMAPK10PKN1PKN2RHEB | |
| SCHEMBL11017894 | 0.80 | CHEK2 (0.43) | AMY1ACHEK2 | |
| SCHEMBL11019649 | 0.80 | RHEB (0.44) | AMY1APKN1PKN2RHEB | |
| SCHEMBL11021667 | 0.80 | AMY1A (0.38) | AMY1APKN1PKN2RHEBCHEK2 | |
| SCHEMBL11016456 | 0.80 | CHEK2 (0.44) | AMY1ACHEK2 | |
| SCHEMBL10417490 | 0.77 | PDE5A (0.43) | AMY1A | |
| Hydrochloric Acid SCHEMBL10415973 | 0.76 | PDE5A (0.44) | AMY1A | |
| SCHEMBL10763275 | 0.74 | MAPK10 (0.42) | MAPK10 | |
| SCHEMBL10762222 | 0.73 | AMY1A (0.41) | AMY1AMAPK10PKN1PKN2RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |