Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 18/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016884 | 0.93 | CHEK2 (0.41) | CHEK2MMP2MMP13AMY1A | |
| SCHEMBL11017894 | 0.90 | CHEK2 (0.43) | CHEK2AMY1A | |
| SCHEMBL11019649 | 0.89 | RHEB (0.44) | MMP2MMP13AMY1A | |
| SCHEMBL11022045 | 0.87 | AMY1A (0.47) | CHEK2AMY1A | |
| SCHEMBL11018934 | 0.80 | AMY1A (0.41) | CHEK2AMY1A | |
| SCHEMBL11017084 | 0.79 | ALDH1A1 (0.41) | CHEK2 | |
| SCHEMBL11020728 | 0.77 | AMY1A (0.48) | CHEK2AMY1A | |
| SCHEMBL10417490 | 0.77 | PDE5A (0.43) | AMY1A | |
| SCHEMBL11018142 | 0.76 | AMY1A (0.43) | AMY1A | |
| SCHEMBL11020861 | 0.76 | ATM (0.41) | CHEK2MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148431-A1 | Benzimidazoles, their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1985-07-17 | — | — | EP | disclosed |