Sugi Predict

Sugi Predict / Compounds / SCHEMBL12544697

SCHEMBL12544697

SCHEMBL12544697

C=CCCCCCCC(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.65
▸ LMNA P02545 2/20 0.65
▸ MAPT P10636 3/20 0.52
▸ ABCC4 O15439 1/20 0.52
▸ TSHR P16473 3/20 0.43
▸ CYP3A4 P08684 3/20 0.41
▸ USP2 O75604 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ RECQL P46063 1/20 0.41
▸ EPHX2 P34913 1/20 0.40
▸ LPAR3 Q9UBY5 2/20 0.38
▸ LPAR2 Q9HBW0 1/20 0.38
▸ HDAC1 Q13547 2/20 0.37
▸ HDAC2 Q92769 2/20 0.37
▸ HDAC6 Q9UBN7 2/20 0.37
▸ HDAC8 Q9BY41 2/20 0.37
▸ HDAC3 O15379 1/20 0.37
▸ HPGD P15428 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31240249 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL8951105 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL30822463 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL12543741 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL14984822 0.98 ALDH1A1 (0.61) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL637189 0.92 ALDH1A1 (0.53) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL2422217 0.89 ALDH1A1 (0.65) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL21068702 0.85 ALDH1A1 (0.47) ALDH1A1LMNAMAPTABCC4TSHR
SCHEMBL31307952 0.85 HSD17B10 (0.49) ALDH1A1LMNAMAPTTSHRCYP3A4
SCHEMBL1101944 0.84 LMNA (0.42) ALDH1A1LMNAMAPTABCC4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190284152-A1 Maleinated Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2019-09-19 — — US disclosed
US-10294210-B2 Maleinated derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2019-05-21 — — US disclosed
US-20180111912-A1 Maleinated Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2018-04-26 — — US disclosed
US-9896424-B2 Methods of making sulfurized derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2018-02-20 — — US disclosed
US-9738618-B2 Malienated derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2017-08-22 — — US disclosed
US-20160355492-A1 Methods of Making Sulfurized Derivatives ELEVANCE RENEWABLE SCIENCES, INC. (US) 2016-12-08 — — US disclosed
CN-103562362-B The monomer of functionalization 艾勒旺斯可再生科学公司 2016-09-14 — — CN disclosed
US-9334347-B2 Functionalized monomers and polymers ELEVANCE RENEWABLE SCIENCES, INC. (US) 2016-05-10 — — US disclosed
US-9012385-B2 Terpene derived compounds ELEVANCE RENEWABLE SCIENCES, INC. (US) 2015-04-21 — — US disclosed
US-20140357539-A1 FUNCTIONALIZED MONOMERS AND POLYMERS WILMAR TRADING PTE LTD (SG) 2014-12-04 — — US disclosed
US-20120283156-A1 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES 2012-11-08 — — US disclosed
US-20120277133-A1 FUNCTIONALIZED POLYMERS ELEVANCE RENEWABLE SCIENCES, INC. 2012-11-01 — — US disclosed
US-20120264662-A1 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES 2012-10-18 — — US disclosed
US-20120264664-A1 MALIENATED DERIVATIVES WILMAR TRADING PTE LTD (SG) 2012-10-18 — — US disclosed
WO-2012129490-A2 FUNCTIONALIZED POLYMERS ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 — — WO disclosed
WO-2012128788-A1 FUNCTIONALIZED MONOMERS AND POLYMERS ELEVANCE RENEWABLE SCIENCES, INC. (US) 2012-09-27 — — WO disclosed
WO-2012129479-A2 MALIENATED DERIVATIVES ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 — — WO disclosed
US-20120245063-A1 FUNCTIONALIZED MONOMERS AND POLYMERS WILMAR TRADING PTE LTD (SG) 2012-09-27 — — US disclosed
WO-2012129477-A1 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 — — WO disclosed
WO-2012129482-A2 FUNCTIONALIZED MONOMERS ELEVANCE RENEWABLE SCIENCES (US) 2012-09-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120277133-A1 FUNCTIONALIZED POLYMERS PARG, PUF60, ADH1C ALDH1A1 428/4885LMNA 2091/4885MAPT 655/4885
US-20120264662-A1 FUNCTIONALIZED MONOMERS MEP1A, MLEC, ADH1A ALDH1A1 83/4885LMNA 3186/4885MAPT 1894/4885
US-20180111912-A1 Maleinated Derivatives SMOX, SRM, PADI2 ALDH1A1 383/4885LMNA 1847/4885MAPT 1493/4885
US-20120245063-A1 FUNCTIONALIZED MONOMERS AND POLYMERS PUF60, FGB, MSN ALDH1A1 562/4885LMNA 2878/4885MAPT 1386/4885
US-20190284152-A1 Maleinated Derivatives SMOX, SRM, PADI2 ALDH1A1 383/4885LMNA 1847/4885MAPT 1493/4885
US-20120283156-A1 FUNCTIONALIZED MONOMERS MEP1A, MLEC, ELANE ALDH1A1 341/4885LMNA 2954/4885MAPT 3158/4885
US-20160355492-A1 Methods of Making Sulfurized Derivatives GPX4, CBS, ESD ALDH1A1 769/4885LMNA 4738/4885MAPT 2790/4885
US-10294210-B2 Maleinated derivatives SMOX, SRM, PADI2 ALDH1A1 385/4885LMNA 1892/4885MAPT 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.