Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019682 | 0.80 | MAPT (0.40) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750432 | 0.80 | HRH3 (0.48) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11019035 | 0.77 | HRH3 (0.48) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750259 | 0.75 | MAPT (0.46) | MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL9750449 | 0.75 | MAPT (0.40) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9750274 | 0.71 | MAOB (0.43) | HRH3NPC1RAB9AMAOBSMN1; SMN2 | |
| SCHEMBL9750285 | 0.70 | HRH3 (0.43) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4602669 | 0.70 | MPI (0.38) | MEN1KMT2ATDP1 | |
| SCHEMBL10903897 | 0.70 | L3MBTL1 (0.55) | NPC1RAB9AMEN1KMT2AGRM5 | |
| SCHEMBL9750421 | 0.69 | ACHE (0.42) | KMT2AMAOBTP53ALOX5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120858-A | Condensation of 2-methyleneindoline and formic acid in acetic anhydride | MILES INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0058863-B1 | PROCESS FOR THE PREPARATION OF TRIMETHINE DYESTUFFS | BAYER AG (DE) | 1985-01-23 | — | — | EP | disclosed |
| US-4419511-A | Process for the preparation of trimethine dyestuffs | BAYER AKTIENGESELLSCHAFT (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0058863-A1 | Process for the preparation of trimethine dyestuffs | BAYER AG (DE) | 1982-09-01 | — | — | EP | disclosed |