Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DNM2 | P50570 | 4/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CYP4Z1 | Q86W10 | 4/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250722 | 0.86 | SLC9A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL11709141 | 0.70 | LMNA (0.31) | TSHR | |
| SCHEMBL11276030 | 0.66 | MAOB (0.34) | MEN1KMT2A | |
| SCHEMBL11882961 | 0.60 | LMNA (0.31) | TSHR | |
| O-Xylene SCHEMBL28129610 | 0.60 | CHRM2 (0.60) | SIGMAR1GRIN1GRIN2AALDH1A1TSHR | |
| Biphenyl SCHEMBL5716029 | 0.60 | SIGMAR1 (0.66) | SIGMAR1GRIN1GRIN2AALDH1A1TSHR | |
| Biphenyl SCHEMBL22832517 | 0.60 | SIGMAR1 (0.66) | SIGMAR1GRIN1GRIN2AALDH1A1TSHR | |
| SCHEMBL4625413 | 0.59 | ALDH1A1 (0.54) | SIGMAR1ALDH1A1TSHRSMN1; SMN2HRH4 | |
| Benzene SCHEMBL28999842 | 0.58 | TSHR (0.77) | SIGMAR1ALDH1A1TSHRHRH4HRH3 | |
| Benzene SCHEMBL28999857 | 0.58 | TSHR (0.77) | SIGMAR1ALDH1A1TSHRHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066303-B1 | 2-AZIDOMETHYL-1,4-BENZODIAZEPINES, THEIR SALTS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Kali-Chemie Pharma GmbH (DE) | 1985-06-19 | — | — | EP | disclosed |