Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709141 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL11389444 | 0.78 | MAPT (0.33) | — | |
| SCHEMBL9527213 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL3523519 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL1649060 | 0.75 | TSHR (0.38) | MAOBMEN1KMT2AATM | |
| SCHEMBL11868744 | 0.74 | MAPT (0.38) | MEN1KMT2A | |
| SCHEMBL6610178 | 0.72 | LMNA (0.40) | MEN1KMT2A | |
| SCHEMBL5804474 | 0.72 | NPC1 (0.33) | — | |
| SCHEMBL4250722 | 0.72 | SLC9A1 (0.38) | MEN1KMT2A | |
| SCHEMBL8423853 | 0.69 | P2RX4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313943-A | 7-Chloro-2,3-dihydro-5-phenyl-1-propargyl-1H-1,4-benzodiazepine-2-one, and a pharmaceutical composition thereof | L. ZAMBELETTI S.P.A., (IT) | 1982-02-02 | — | — | US | disclosed |