SCHEMBL1102406

SCHEMBL1102406

CC(C)c1c2ccccc2cc2ccncc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
HTT P42858 2/20 0.49
POLB P06746 1/20 0.49
RAD52 P43351 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.45
TOP2A P11388 1/20 0.43
TNF P01375 1/20 0.41
ACHE P22303 1/20 0.41
CYP11B1 P15538 2/20 0.40
MAOA P21397 3/20 0.39
TDO2 P48775 2/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
IKBKB O14920 1/20 0.37
AURKA O14965 1/20 0.37
CHUK O15111 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PIM1 P11309 1/20 0.37
TOP1 P11387 1/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13338344 0.90 KDM4E (0.41) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL40806 0.83 ALDH1A1 (0.44) KDM4EACHEMAOAALDH1A1HPGD
SCHEMBL13706082 0.80 MAOA (0.47) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL10072720 0.78 TOP2A (0.55) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL13193050 0.75 HTR2A (0.41) KDM4EHTTPOLBRAD52TOP2A
SCHEMBL30641851 0.73 KDM4E (0.53) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL12887711 0.73 KDM4E (0.53) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL13445401 0.73 KDM4E (0.53) KDM4EHTTPOLBRAD52NCOA3
SCHEMBL13408659 0.72 CCR1 (0.50) KDM4EHTTPOLBALDH1A1IDO1
SCHEMBL13615692 0.72 CYP3A4 (0.46) KDM4EHTTPOLBRAD52ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-25 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 KDM4E 3940/4885HTT 3990/4885POLB 1974/4885
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 KDM4E 4170/4885HTT 2470/4885POLB 2404/4885
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 KDM4E 3671/4885HTT 3379/4885POLB 1819/4885
US-20100072888-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOC2, SCO2, C1S KDM4E 4319/4885HTT 1720/4885POLB 2943/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 KDM4E 4525/4885HTT 2108/4885POLB 2990/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A KDM4E 4138/4885HTT 4013/4885POLB 913/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 KDM4E 2780/4885HTT 2003/4885POLB 3001/4885
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 KDM4E 3298/4885HTT 3566/4885POLB 1309/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 KDM4E 3367/4885HTT 4390/4885POLB 2825/4885
US-20100032658-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 KDM4E 3009/4885HTT 4130/4885POLB 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.