SCHEMBL1102474

SCHEMBL1102474

CC(C)c1ccc2c(c1)N(c1ccccc1)c1ccccc1C=C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.38
P2RX4 Q99571 6/20 0.37
P2RX1 P51575 2/20 0.37
P2RX3 P56373 2/20 0.37
P2RX7 Q99572 2/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
NR1H3 Q13133 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
NOTUM Q6P988 2/20 0.33
MIF P14174 1/20 0.33
NPSR1 Q6W5P4 2/20 0.33
PTBP1 P26599 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FAAH O00519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20624617 0.85 MGLL (0.52) MGLLP2RX4P2RX1P2RX3P2RX7
SCHEMBL1102443 0.82 MGLL (0.39) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL13408655 0.80 POLB (0.42) P2RX4P2RX1P2RX3P2RX7ALDH1A1
SCHEMBL12320963 0.79 MGLL (0.46) MGLLP2RX4P2RX1P2RX3P2RX7
SCHEMBL1102446 0.79 NR1H3 (0.42) P2RX4P2RX1P2RX3P2RX7LMNA
SCHEMBL12901308 0.79 HDAC3 (0.38) MGLLP2RX4P2RX1P2RX3P2RX7
SCHEMBL1102509 0.76 NR1H3 (0.40) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL13338349 0.76 ALDH1A1 (0.41) MGLLALDH1A1LMNATSHRNR1H3
SCHEMBL16598115 0.76 OPRK1 (0.42) MGLLP2RX4ALDH1A1LMNATSHR
SCHEMBL13352987 0.76 GNG2 (0.47) MGLLP2RX4ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same GRACEL DISPLAY INC. (KR) 2010-04-22 US disclosed
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-03-04 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 MGLL 1873/4885P2RX4 1386/4885P2RX1 1577/4885
US-20100096982-A1 Novel organic electroluminescent compounds and organic electrouminescent device using the same OCIAD1, OR10J3, ORMDL3 MGLL 1347/4885P2RX4 976/4885P2RX1 821/4885
US-20090230852-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OXER1, L1CAM, RPL41 MGLL 2571/4885P2RX4 1156/4885P2RX1 508/4885
US-20100051106-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same RPL36, RPL39, RPL36A MGLL 4337/4885P2RX4 2539/4885P2RX1 2098/4885
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 MGLL 2682/4885P2RX4 1033/4885P2RX1 1355/4885
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 MGLL 717/4885P2RX4 1538/4885P2RX1 1627/4885
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 MGLL 1501/4885P2RX4 1489/4885P2RX1 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.