SCHEMBL110300

SCHEMBL110300

NN(C(=O)C=CC(=O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.47
NPSR1 Q6W5P4 2/20 0.45
HCAR2 Q8TDS4 2/20 0.42
HDAC3 O15379 1/20 0.42
TNKS O95271 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
TNKS2 Q9H2K2 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
MAPT P10636 2/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.39
ALDH1A1 P00352 5/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30764040 0.83 TRPM8 (0.66) TRPM8NPSR1HCAR2HDAC3TNKS
SCHEMBL11532896 0.81 HCAR2 (0.44) HCAR2MAPTALDH1A1HTTRAB9A
Fumaric Acid SCHEMBL29144720 0.81 HCAR2 (0.46) TRPM8NPSR1HCAR2HDAC3TNKS
SCHEMBL11669536 0.79 NPSR1 (0.48) TRPM8NPSR1MAPTALDH1A1NPC1
SCHEMBL11527666 0.78 ALDH1A1 (0.51) MAPTALDH1A1HTTRAB9AKMT2A
SCHEMBL7864460 0.78 NPSR1 (0.46) TRPM8NPSR1ALDH1A1NPC1POLB
SCHEMBL837372 0.78 TRPM8 (0.44) TRPM8NPSR1HCAR2HDAC3TNKS
SCHEMBL837373 0.78 TRPM8 (0.44) TRPM8NPSR1HCAR2HDAC3TNKS
SCHEMBL3279797 0.78 TRPM8 (0.44) TRPM8NPSR1HCAR2HDAC3TNKS
Fumaric Acid SCHEMBL21145270 0.76 HCAR2 (0.50) TRPM8NPSR1HCAR2HDAC3TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714985-A1 DUAL CURE RESIN COMPOSITION Henkel AG & Co. KGaA (DE) 2026-03-25 EP disclosed
US-20260049201-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2026-02-19 US disclosed
EP-4269462-B1 TWO COMPONENT (2K) ACRYLIC COMPOSITION COMPRISING A THERMOPLASTIC POLYURETHANE HENKEL AG & CO KGAA (DE) 2026-01-28 EP disclosed
WO-2025118203-A1 BONDED STRUCTURE COMPRISING AN ELECTROCHEMICALLY DEBONDABLE FILM ADHESIVE HENKEL AG & CO. KGAA (DE) 2025-06-12 WO disclosed
WO-2025119658-A1 ELECTROCHEMICALLY DEBONDABLE ADHESIVE FILM HENKEL AG & CO. KGAA (DE) 2025-06-12 WO disclosed
EP-4567085-A1 ELECTROCHEMICALLY DEBONDABLE ADHESIVE FILM Henkel AG & Co. KGaA (DE) 2025-06-11 EP disclosed
EP-4200344-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL AG & CO KGAA (DE) 2025-05-07 EP disclosed
US-20250051612-A1 TWO COMPONENT (2K) ACRYLIC COMPOSITION COMPRISING A BIO-RENEWABLE MONOMER HENKEL AG & CO KGAA (DE) 2025-02-13 US disclosed
US-20250043124-A1 TWO COMPONENT (2K) ACRYLIC COMPOSITION COMPRISING A THERMOPLASTIC POLYURETHANE HENKEL AG & CO. KGAA (DE) 2025-02-06 US disclosed
CN-119095925-A Two-component (2K) acrylic composition comprising biorenewable monomers 汉高股份有限及两合公司 2024-12-06 CN disclosed
EP-2170963-A2 NOVEL ADDUCTS USEFUL AS CURE COMPONENTS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel Corporation (US) 2010-04-07 EP disclosed
WO-2009137448-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
WO-2009137444-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
WO-2009137455-A2 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-11-12 WO disclosed
US-20090278084-A1 Cure accelerators for anaerobic curable compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
US-20090281335-A1 Cure Accelerators for Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-11-12 US disclosed
WO-2009014688-A2 NOVEL ADDUCTS USEFUL AS CURE COMPONENTS FOR ANAEROBIC CURABLE COMPOSITIONS HENKEL CORPORATION (US) 2009-01-29 WO disclosed
US-20090025874-A1 Novel Adducts Useful As Cure Components For Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-01-29 US disclosed
US-6835762-B1 Cure accelerators for anaerobic curable compositions HENKEL CORPORATION 2004-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090277356-A1 Cure Accelerators for Anaerobic Curable Compositions ACLY, ACAD9, CCNY TRPM8 4792/4885NPSR1 4777/4885HCAR2 924/4885
US-20090278084-A1 Cure accelerators for anaerobic curable compositions EGLN3, INO80, IDH2 TRPM8 4842/4885NPSR1 4673/4885HCAR2 865/4885
US-20260049201-A1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS AHCY, AHCYL1, ALKBH3 TRPM8 4809/4885NPSR1 3532/4885HCAR2 73/4885
US-20090281335-A1 Cure Accelerators for Anaerobic Curable Compositions CAT, MRM1, ACLY TRPM8 4711/4885NPSR1 4573/4885HCAR2 1405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.