Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024548 | 0.94 | MTNR1B (0.42) | SLC18A2KCNH2 | |
| SCHEMBL11026816 | 0.79 | KMT2A (0.46) | KCNH2 | |
| SCHEMBL11216819 | 0.76 | KMT2A (0.43) | KCNH2 | |
| SCHEMBL11029433 | 0.72 | SLC18A2 (0.43) | SLC18A2KCNH2 | |
| SCHEMBL4664890 | 0.69 | MTNR1B (0.40) | — | |
| SCHEMBL9876918 | 0.68 | SLC18A2 (0.49) | SLC18A2 | |
| SCHEMBL10994286 | 0.67 | ALDH1A1 (0.55) | — | |
| SCHEMBL10993438 | 0.65 | HTT (0.45) | — | |
| SCHEMBL28328103 | 0.64 | ABCB1 (0.60) | SLC18A2KCNH2 | |
| SCHEMBL14548187 | 0.63 | FAAH (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086678-B1 | PROCESS FOR THE PREPARATION OF 2-ACYL-1,3,4,6,7,11B-2H-HEXAHYDRO-4-PYRAZINO(2,1-A)ISOQUINOLINONES AND INTERMEDIATES | ELF SANOFI (FR) | 1985-07-03 | — | — | EP | disclosed |
| EP-0086678-A1 | Process for the preparation of 2-acyl-1,3,4,6,7,11b-2H-hexahydro-4-pyrazino(2,1-a)isoquinolinones and intermediates | ELF SANOFI (FR) | 1983-08-24 | — | — | EP | disclosed |