Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749410 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP3A4RECQLKMT2AMAPK1 | |
| SCHEMBL10930293 | 0.73 | RIPK1 (0.60) | CYP3A4KMT2AMEN1MAPK1TSHR | |
| SCHEMBL10932439 | 0.72 | RIPK1 (0.59) | KMT2AMEN1LMNAALDH1A1RIPK1 | |
| SCHEMBL24710855 | 0.72 | CYP1A2 (0.44) | CYP1A2CYP3A4RECQLKMT2AMAPK1 | |
| SCHEMBL7570207 | 0.71 | GABRA1 (0.34) | LMNATSHRPOLBMAPT | |
| SCHEMBL10930164 | 0.70 | GPR139 (0.39) | CYP1A2CYP3A4RECQLKMT2AMEN1 | |
| SCHEMBL3275686 | 0.69 | RIPK1 (0.38) | KMT2ASMN1; SMN2MAPK1TSHRCYP2C19 | |
| SCHEMBL11047589 | 0.69 | ADRB2 (0.39) | CYP1A2CYP3A4RECQLKMT2AMEN1 | |
| SCHEMBL6435840 | 0.69 | PDK1 (0.41) | SMN1; SMN2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL24222570 | 0.68 | HDAC1 (0.44) | CYP1A2CYP3A4RECQLKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59039864-A | — | — | None | — | — | JP | disclosed |
| JP-S5939864-A | UREA DERIVATIVE AND SELECTIVE HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | JAPAN CARLIT CO LTD:THE | 1984-03-05 | — | — | JP | disclosed |