Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNTT | P04053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313635 | 0.84 | FFAR3 (0.46) | FFAR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8611028 | 0.65 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7845674 | 0.62 | FFAR3 (0.64) | FFAR3KDM4EALDH1A1HPGD | |
| SCHEMBL7148358 | 0.61 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL5816251 | 0.60 | KDM4E (0.57) | FFAR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL11256668 | 0.60 | ALDH1A1 (0.57) | KDM4EALDH1A1GAAHPGDDNTT | |
| SCHEMBL7107070 | 0.57 | LMNA (0.69) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL2576010 | 0.56 | LMNA (0.50) | FFAR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL8521929 | 0.56 | ALDH1A1 (0.50) | FFAR3KDM4EALDH1A1GAAHPGD | |
| SCHEMBL7152871 | 0.55 | ALDH1A1 (0.78) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0059291-B1 | ANTIHYPERTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-03-27 | — | — | EP | claimed |