Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912854 | 0.84 | KDM4E (0.45) | KDM4EF13A1MAPTALDH1A1LMNA | |
| SCHEMBL10592850 | 0.76 | KDM4E (0.84) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL514228 | 0.74 | QPCT (0.49) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11040313 | 0.74 | KDM4E (0.51) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11713261 | 0.72 | KDM4E (0.89) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10066080 | 0.72 | KDM4E (0.66) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5503996 | 0.72 | KDM4E (0.53) | KDM4EF13A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL4482880 | 0.72 | METAP2 (0.49) | KDM4ESMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL29938013 | 0.72 | CA2 (0.46) | ALDH1A1LMNAHPGD | |
| SCHEMBL2028394 | 0.71 | TGM2 (0.52) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465841-A | ANTISECRETORY, ANTIULCER AGENTS | INSTITUTO DE ANGELI S.P.A. (IT) | 1984-08-14 | — | — | US | disclosed |
| US-4386099-A | GASTROINTESTINAL DISORDERS, ULCERS | ISTITUTO DE ANGELI S.P.A. (IT) | 1983-05-31 | — | — | US | disclosed |