Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.35 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.36 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.36 |
| ▸ | RPS17 | P08708 | 1/20 | 0.36 |
| ▸ | RPSA | P08865 | 1/20 | 0.36 |
| ▸ | RPS2 | P15880 | 1/20 | 0.36 |
| ▸ | RPL35A | P18077 | 1/20 | 0.36 |
| ▸ | RPL7 | P18124 | 1/20 | 0.36 |
| ▸ | RPL17 | P18621 | 1/20 | 0.36 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.36 |
| ▸ | RPS3 | P23396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164396 | 0.92 | ACHE (0.42) | GAAACHEHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL11043092 | 0.85 | GSR (0.46) | ALDH1A1MAPK1MAPTNPSR1TDP1 | |
| Alcohol SCHEMBL11040658 | 0.78 | PKM (0.32) | GAACA1CA2ACHEHSD17B10 | |
| SCHEMBL11040661 | 0.76 | ACHE (0.35) | GAACA1CA2ACHEHSD17B10 | |
| SCHEMBL9337987 | 0.75 | ACHE (0.43) | GAAACHEHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL2461330 | 0.74 | IGF1R (0.37) | CA1CA2MMP2ALDH1A1MAPT | |
| SCHEMBL2461283 | 0.74 | IGF1R (0.37) | CA1CA2MMP2ALDH1A1MAPT | |
| SCHEMBL6258107 | 0.74 | ALDH1A1 (0.53) | CA1CA2RPLP1RPLP0RPS17 | |
| SCHEMBL11041781 | 0.74 | GRIA4 (0.50) | GAACA1CA2MMP1MMP2 | |
| SCHEMBL3336779 | 0.73 | GSR (0.55) | ALDH1A1MAPK1MAPTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |