Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041218 | 0.92 | NPC1 (0.50) | SIRT2PPARAPPARGTDP1EPHX2 | |
| SCHEMBL11041569 | 0.87 | HPGD (0.53) | TDP1NPC1RAB9AHTT | |
| SCHEMBL11041771 | 0.86 | RAB9A (0.55) | SIRT2TDP1EPHX2NPC1RAB9A | |
| SCHEMBL11046557 | 0.85 | PSMB5 (0.48) | SIRT2NPC1THRBHTTLMNA | |
| SCHEMBL11038572 | 0.85 | LMNA (0.53) | SIRT2THRBHTTLMNA | |
| SCHEMBL11037929 | 0.84 | SIRT2 (0.55) | SIRT2TDP1RAB9ATHRBLMNA | |
| SCHEMBL11039230 | 0.84 | SIRT2 (0.45) | SIRT2TDP1RAB9ALMNA | |
| SCHEMBL9799045 | 0.84 | RAB9A (0.53) | SIRT2NPC1RAB9A | |
| SCHEMBL11041787 | 0.84 | ALDH1A1 (0.48) | SIRT2TDP1THRBF10CACNA1B | |
| SCHEMBL11037849 | 0.84 | MEN1 (0.44) | SIRT2TDP1NPC1RAB9ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |