SCHEMBL1104140

SCHEMBL1104140

C=C(C)COOCCOC(=O)c1cc(NC(=O)C(C)(C)CC)cc(C(=O)OCCOOCC(=C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 1/20 0.38
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
MAPT P10636 2/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RAB9A P51151 1/20 0.34
CNR1 P21554 5/20 0.34
CNR2 P34972 5/20 0.34
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
PDK1 Q15118 1/20 0.33
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
PDK4 Q16654 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104139 0.89 RAB9A (0.46) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL1104172 0.76 KDM4E (0.58) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL13756079 0.73 RAB9A (0.49) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL1104091 0.72 THRB (0.33)
SCHEMBL14271607 0.71 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2AMEN1TSHR
SCHEMBL1104128 0.71 GPR174 (0.45) ALDH1A1KMT2AMEN1MAPTLMNA
SCHEMBL13756074 0.70 RAB9A (0.46) ALDH1A1KMT2AMEN1MAPTTSHR
SCHEMBL1104099 0.69 RIPK1 (0.36)
SCHEMBL1948564 0.69 CNR2 (0.50) ALDH1A1KMT2AMEN1LMNACNR1
SCHEMBL14271601 0.68 ALDH1A1 (0.43) ALDH1A1KDM4EKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-7771916-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2010-08-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed