SCHEMBL1104265

SCHEMBL1104265

CC(CO)(CO)COC(=O)CCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 4/20 0.41
KDM6B O15054 2/20 0.41
KDM5C P41229 2/20 0.41
PHF8 Q9UPP1 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
LMNA P02545 4/20 0.38
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
SLC15A2 Q16348 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TSHR P16473 2/20 0.33
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PAM P19021 2/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
VCAM1 P19320 1/20 0.31
FFAR3 O14843 1/20 0.31
HDAC3 O15379 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12192458 0.89 TSHR (0.44) LMNAALDH1A1TSHRHSD17B10PAM
SCHEMBL1104242 0.89 TSHR (0.48) LMNAALDH1A1TSHRPAMVCAM1
SCHEMBL15478915 0.86 KDM6B (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL8700063 0.84 EGLN1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL10399933 0.82 ALDH1A1 (0.44) LMNAALDH1A1TSHRADRA1AHSD17B10
SCHEMBL7349207 0.82 EGLN1 (0.42) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL9989221 0.81 EGLN1 (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL26114080 0.80 LMNA (0.33) LMNAHSD17B10
Ethylene Glycol SCHEMBL28166943 0.80 EGLN1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL2139466 0.79 MAPK1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4096127-A Anionic polyurethanes AKZONA INCORPORATED (US) 1978-06-20 US claimed
EP-2698411-B9 MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL INC (US) 2017-12-06 EP disclosed
EP-2698411-B1 MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL INC (US) 2017-02-01 EP disclosed
EP-2698412-B1 MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL INC (US) 2016-10-12 EP disclosed
US-8927195-B2 Photosensitive composition, planographic printing plate precursor, polyurethane, and method for producing polyurethane FUJIFILM CORPORATION (JP) 2015-01-06 US disclosed
US-8927195-B2 Photosensitive composition, planographic printing plate precursor, polyurethane, and method for producing polyurethane FUJIFILM CORPORATION (JP) 2015-01-06 US disclosed
EP-2810784-A1 RESIN COMPOSITION FOR LASER-ENGRAVABLE FLEXOGRAPHIC PRINTING PLATE, ORIGINAL PLATE FOR LASER-ENGRAVABLE FLEXOGRAPHIC PRINTING PLATE AND METHOD FOR PRODUCTION THEREOF, AND FLEXOGRAPHIC PRINTING PLATE AND METHOD FOR PRODUCTION THEREOF Fujifilm Corporation (JP) 2014-12-10 EP disclosed
US-20140338550-A1 RESIN COMPOSITION FOR LASER-ENGRAVABLE FLEXOGRAPHIC PRINTING PLATE, FLEXOGRAPHIC PRINTING PLATE PRECURSOR FOR LASER-ENGRAVABLE AND PROCESS FOR PRODUCING SAME, AND FLEXOGRAPHIC PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2014-11-20 US disclosed
US-20140338550-A1 RESIN COMPOSITION FOR LASER-ENGRAVABLE FLEXOGRAPHIC PRINTING PLATE, FLEXOGRAPHIC PRINTING PLATE PRECURSOR FOR LASER-ENGRAVABLE AND PROCESS FOR PRODUCING SAME, AND FLEXOGRAPHIC PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2014-11-20 US disclosed
US-20140134540-A1 PHOTOSENSITIVE COMPOSITION, PLANOGRAPHIC PRINTING PLATE PRECURSOR, POLYURETHANE, AND METHOD FOR PRODUCING POLYURETHANE FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042532-A2 Polymerizable composition and planographic printing plate precursor using the same, alkalisoluble polyrethane resin, an process for producing diol compound FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-20090053653-A1 POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-20090053653-A1 POLYMERIZABLE COMPOSITION AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-7491487-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed
US-7491487-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-02-17 US disclosed
US-7455954-B2 Lithographic printing plate precursor and polymerizable composition FUJIFILM CORPORATION (JP) 2008-11-25 US disclosed
US-4777224-A POLYETHERURETHANES, SIZING COMPOSITION AKZO NV (NL) 1988-10-11 US disclosed
US-4096127-A Anionic polyurethanes AKZONA INCORPORATED (US) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087785-A1 POLYMERIZABLE COMPOSITION AND PLANOGRAPHIC PRINTING PLATE PRECURSOR USING THE SAME, ALKALI-SOLUBLE POLYURETHANE RESIN, AND PROCESS FOR PRODUCING DIOL COMPOUND PAH, RPN1, RER1 EGLN1 422/4885KDM6B 1990/4885KDM5C 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.