SCHEMBL9989221

SCHEMBL9989221

CC(C)(C)COC(=O)CCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 5/20 0.45
KDM5C P41229 3/20 0.45
PHF8 Q9UPP1 3/20 0.45
KDM2A Q9Y2K7 3/20 0.45
KDM6B O15054 2/20 0.45
LMNA P02545 3/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
SUCNR1 Q9BXA5 1/20 0.41
SLC15A2 Q16348 1/20 0.39
ALDH1A1 P00352 1/20 0.37
TSHR P16473 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA1A P35348 1/20 0.37
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
PAM P19021 2/20 0.35
FFAR3 O14843 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL2856532 0.94 FFAR3 (0.41) EGLN1KDM5CPHF8KDM2AKDM6B
Ethylene Glycol SCHEMBL28166943 0.94 EGLN1 (0.41) EGLN1KDM5CPHF8KDM2AKDM6B
SCHEMBL2485813 0.91 ADRA2A (0.42) LMNAALDH1A1TSHRADRA2AADRA1A
SCHEMBL28682096 0.87 TSHR (0.54) LMNAALDH1A1TSHRPAMOR51E2
SCHEMBL852014 0.87 TSHR (0.48) LMNAALDH1A1TSHRPAMOR51E2
SCHEMBL7680019 0.85 PAM (0.48) LMNAALDH1A1TSHRPAMOR51E2
Glutarate SCHEMBL7569753 0.85 TSHR (0.52) LMNAALDH1A1TSHRPAMOR51E2
SCHEMBL7047237 0.85 PAM (0.48) LMNAALDH1A1TSHRPAMOR51E2
SCHEMBL27804161 0.85 PAM (0.48) LMNAALDH1A1TSHRPAMOR51E2
Ethylene SCHEMBL30631590 0.84 TSHR (0.45) LMNAALDH1A1TSHRPAMOR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116769231-A Recycling method for mild and efficient selective hydrolysis of waste high polymer material based on polyester 四川大学 2023-09-19 CN claimed
WO-2011158102-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF POLYESTER RESINS SUITABLE AS BINDERS FOR COMPATIBLE THERMOSETTING PAINTS ANS PAINTS BASED ON SAID POLYESTER RESINS ALCEA - AZIENDA LOMBARDA COLORI E AFFINI S.R.L. (IT) 2011-12-22 WO claimed
CN-114127144-B Transition metal chelating polyol blends for polyurethane polymers 陶氏环球技术有限责任公司 2024-11-22 CN disclosed
US-20240228503-A1 TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2024-07-11 US disclosed
CN-116769231-A Recycling method for mild and efficient selective hydrolysis of waste high polymer material based on polyester 四川大学 2023-09-19 CN disclosed
EP-3818047-B1 NOVEL COMPOUNDS FOR CONTROLLING ARTHROPODS BAYER ANIMAL HEALTH GMBH (DE) 2022-07-27 EP disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
CN-106574057-A High melt strength polypropylene and extrusion process for maintaining melt strength 埃克森美孚化学专利公司 2017-04-19 CN disclosed
US-7417156-B2 Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers JOHNS HOPKINS UNIVERSITY (US) 2008-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228503-A1 TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS SSB, CGAS, STING1 EGLN1 3556/4885KDM5C 1886/4885PHF8 3997/4885
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B EGLN1 4213/4885KDM5C 4660/4885PHF8 4260/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 EGLN1 4439/4885KDM5C 4713/4885PHF8 4544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.