Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PAM | P19021 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349190 | 0.91 | ADRA2A (0.39) | LMNACYP1A2TSHRADRA2AADRA1A | |
| SCHEMBL9989221 | 0.83 | EGLN1 (0.45) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| SCHEMBL8700063 | 0.82 | EGLN1 (0.41) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| SCHEMBL1104265 | 0.82 | EGLN1 (0.41) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| SCHEMBL27897028 | 0.81 | ALDH1A1 (0.46) | LMNAALDH1A1CYP1A2TSHRPAM | |
| SCHEMBL12328700 | 0.80 | CYP1A2 (0.38) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| Hydrochloric Acid SCHEMBL11556216 | 0.79 | ALDH1A1 (0.44) | LMNAALDH1A1CYP1A2TSHRPAM | |
| SCHEMBL26381739 | 0.79 | EGLN1 (0.42) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| SCHEMBL11912289 | 0.78 | LMNA (0.45) | EGLN1KDM5CPHF8KDM2AKDM6B | |
| SCHEMBL1405339 | 0.78 | LMNA (0.45) | EGLN1KDM5CPHF8KDM2AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344957-A | Amidinoiphenyl-substituted | G.D. SEARLE & CO. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5239113-A | Anticoagulants | MONSANTO COMPANY (US) | 1993-08-24 | — | — | US | disclosed |