Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 4/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4969959 | 0.81 | ALPL (0.65) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL11716674 | 0.81 | ALPL (0.65) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL9795232 | 0.81 | POLB (0.48) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL11309741 | 0.79 | ALDH1A1 (0.42) | POLBL3MBTL1ALPLPLAAALDH1A1 | |
| SCHEMBL10926010 | 0.76 | KDM4C (0.39) | POLBL3MBTL1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12060163 | 0.76 | HMOX1 (0.51) | L3MBTL1TRPA1MEN1KMT2A | |
| SCHEMBL28267245 | 0.75 | PLAA (0.59) | POLBSMN1; SMN2PLAAALDH1A1TRPA1 | |
| SCHEMBL9640838 | 0.73 | MCL1 (0.37) | L3MBTL1SMN1; SMN2ALPLPLAAALDH1A1 | |
| SCHEMBL19925217 | 0.72 | HPGDS (0.53) | POLBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28115922 | 0.71 | KDM4E (0.57) | L3MBTL1SMN1; SMN2ALDH1A1TRPA1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027177-B1 | 1-AZOLYL-1-HALOGEN-ALKAN-2-ONES AND PROCESS FOR THE PREPARATION OF 1-AZOLYL-1-PHENOXY-ALKAN-2-ONES | BAYER AG (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0027177-A1 | 1-Azolyl-1-halogen-alkan-2-ones and process for the preparation of 1-azolyl-1-phenoxy-alkan-2-ones | BAYER AG (DE) | 1981-04-22 | — | — | EP | disclosed |