Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 4/20 | 0.43 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.43 |
| ▸ | ALPG | P10696 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044807 | 0.81 | POLB (0.55) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL11716674 | 0.81 | ALPL (0.65) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL4969959 | 0.81 | ALPL (0.65) | POLBL3MBTL1SMN1; SMN2ALPLPLAA | |
| SCHEMBL28267245 | 0.75 | PLAA (0.59) | POLBSMN1; SMN2PLAAALPGMEN1 | |
| SCHEMBL28115922 | 0.71 | KDM4E (0.57) | L3MBTL1SMN1; SMN2MEN1RECQLKMT2A | |
| SCHEMBL3727754 | 0.71 | BRD4 (0.48) | CYP19A1 | |
| SCHEMBL1509735 | 0.70 | CYP19A1 (0.71) | L3MBTL1PLAAALPGCYP19A1CYP11B1 | |
| SCHEMBL20491004 | 0.70 | CYP3A4 (0.45) | L3MBTL1SMN1; SMN2ALPLPLAAALPG | |
| Hydrochloric Acid SCHEMBL410578 | 0.69 | CYP19A1 (0.69) | L3MBTL1PLAAALPGCYP19A1CYP11B1 | |
| SCHEMBL28306997 | 0.69 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2ALPLPLAAALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032607-A | Enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-07-16 | — | — | US | disclosed |
| US-4866086-A | PHENYLTRIAZOLYL OLEFINIC AROMATASE INHIBITORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-12 | — | — | US | disclosed |
| EP-0299683-A2 | Heterocyclic olefinic compounds and their use as aromatase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-01-18 | — | — | EP | disclosed |