SCHEMBL11045211

SCHEMBL11045211

C=CCNc1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 5/20 0.53
KDM4E B2RXH2 7/20 0.47
ALDH1A1 P00352 6/20 0.47
HPGD P15428 4/20 0.47
PPOX P50336 1/20 0.46
ATIC P31939 1/20 0.46
GLA P06280 1/20 0.45
ALOX12 P18054 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
MAPT P10636 2/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11408024 0.80 CA12 (0.44) CASP3KDM4EALDH1A1CA12CA1
SCHEMBL6341593 0.77 KDM4E (0.58) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL2537623 0.77 ALDH1A1 (0.54) CASP3ALDH1A1CA12CA1CA2
SCHEMBL6141670 0.76 CASP3 (0.44) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL6340923 0.76 KDM4E (0.49) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL9623183 0.74 KDM4E (0.48) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL10282762 0.72 KDM4E (0.59) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL11022780 0.72 MAOA (0.55) CASP3KDM4EALDH1A1HPGDGLA
SCHEMBL4093994 0.72 KDM4E (0.50) CASP3KDM4EALDH1A1HPGDPPOX
SCHEMBL2659189 0.72 KDM4E (0.61) CASP3KDM4EALDH1A1HPGDPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0039719-B1 MOTION PICTURE FILM HAVING DIGITALLY CODED SOUNDTRACK AND METHOD FOR PRODUCTION THEREOF CUSTER, Peter Anderson (US) 1985-10-16 EP disclosed
EP-0039719-A4 MOTION PICTURE FILM HAVING DIGITALLY CODED SOUNDTRACK AND METHOD FOR PRODUCTION THEREOF. CUSTER PETER ANDERSON (US) 1982-03-03 EP disclosed
EP-0039719-A1 MOTION PICTURE FILM HAVING DIGITALLY CODED SOUNDTRACK AND METHOD FOR PRODUCTION THEREOF. CUSTER PETER ANDERSON (US) 1981-11-18 EP disclosed
WO-1981001204-A1 MOTION PICTURE FILM HAVING DIGITALLY CODED SOUNDTRACK AND METHOD FOR PRODUCTION THEREOF CUSTER P 1981-04-30 WO disclosed