SCHEMBL6141670

SCHEMBL6141670

C=CCONc1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 3/20 0.44
KDM4E B2RXH2 5/20 0.43
ALDH1A1 P00352 4/20 0.43
HPGD P15428 2/20 0.43
GLA P06280 1/20 0.42
PPOX P50336 1/20 0.42
ALOX12 P18054 1/20 0.42
KMT2A Q03164 7/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
MEN1 O00255 5/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 3/20 0.40
ATIC P31939 1/20 0.40
EGFR P00533 3/20 0.40
PRKD3 O94806 2/20 0.40
PRKCG P05129 2/20 0.40
PRKCB P05771 2/20 0.40
SRC P12931 2/20 0.40
PRKCA P17252 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11045211 0.76 CASP3 (0.53) CASP3KDM4EALDH1A1HPGDGLA
SCHEMBL11832119 0.73 MAOA (0.61) ALDH1A1HPGDKMT2AMEN1MAPT
SCHEMBL10433957 0.69 RAPGEF4 (0.39) KDM4EALDH1A1HPGDKMT2AMEN1
SCHEMBL10282762 0.69 KDM4E (0.59) CASP3KDM4EALDH1A1HPGDGLA
SCHEMBL24237008 0.68 PPOX (0.52) KDM4EALDH1A1HPGDGLAPPOX
SCHEMBL3145098 0.68 PPOX (0.55) CASP3KDM4EALDH1A1HPGDGLA
SCHEMBL29262768 0.68 KDM4E (0.57) KDM4EALDH1A1HPGDGLAPPOX
SCHEMBL3145102 0.68 PPOX (0.55) KDM4EALDH1A1HPGDGLAPPOX
SCHEMBL6341593 0.67 KDM4E (0.58) CASP3KDM4EALDH1A1HPGDGLA
SCHEMBL28723255 0.67 GABRA1 (0.52) KDM4EALDH1A1HPGDPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000108-B1 AQUEOUS POLYIMIDE PROCESS COMMW SCIENT IND RES ORG (AU) 2005-01-05 EP disclosed
US-6333391-B1 FROM AMINES AND CARBOXYLIC ACIDS OR ANHYDRIDES, IN WATER; COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2001-12-25 US disclosed
EP-1000108-A4 AQUEOUS POLYIMIDE PROCESS COMMW SCIENT IND RES ORG (AU) 2000-10-11 EP disclosed
EP-1000108-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-05-17 EP disclosed
WO-1999006470-A1 AQUEOUS POLYIMIDE PROCESS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-11 WO disclosed
US-5760165-A CURABLE ALLYL POLYMERS; HEAT RESISTANCE, STABILITY; ADHESIVES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (CSIRO) (AU) 1998-06-02 US disclosed