SCHEMBL11046095

SCHEMBL11046095

Cc1c(C)c(O)c(NCCO)c(C)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 3/20 0.34
POLB P06746 3/20 0.34
KDM4E B2RXH2 2/20 0.34
GLA P06280 2/20 0.34
MITF O75030 1/20 0.34
LMNA P02545 1/20 0.34
TTR P02766 1/20 0.34
RAD52 P43351 1/20 0.34
RAB9A P51151 1/20 0.34
HPGD P15428 1/20 0.33
APP P05067 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718684 0.70 NUDT1 (0.31)
SCHEMBL8707687 0.67 CYP3A4 (0.36) TSHR
SCHEMBL17662344 0.67 MAPK1 (0.36) GAAMAPK1MEN1KMT2ATSHR
SCHEMBL456751 0.66 ALDH1A1 (0.35) GAAMAPK1MEN1KMT2ATSHR
SCHEMBL6848565 0.66 ALDH1A1 (0.35) GAAMAPK1MEN1KMT2ATSHR
Durohydroquinone SCHEMBL69786 0.66 ALOX5 (0.38) ALDH1A1HPGDACHEALOX5
SCHEMBL1004807 0.65 ALDH1A1 (0.46) GAAMAPK1MEN1KMT2AALDH1A1
SCHEMBL2354474 0.65 RAPGEF4 (0.48) GAAMAPK1MEN1KMT2ATSHR
SCHEMBL7571211 0.64 KDM4E (0.39) GAAMAPK1MEN1KMT2ATSHR
SCHEMBL397768 0.62 ALOX5 (0.36) ALDH1A1ACHEALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59220732-A None JP disclosed
JP-S59220732-A PHOTORESIST DEVELOPING SOLUTION TOSHIBA CORP 1984-12-12 JP disclosed