Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.76 |
| ▸ | PGR | P06401 | 2/20 | 0.74 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.67 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | IL1RN | P18510 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.58 |
| ▸ | WDR5 | P61964 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133710 | 0.88 | CES1 (0.81) | MEN1KMT2APGRCES1ALDH1A1 | |
| SCHEMBL4651308 | 0.85 | CES1 (0.65) | MEN1KMT2APGRITGA1CES1 | |
| SCHEMBL9285136 | 0.84 | WDR5 (0.74) | MEN1KMT2APGRCES1ALDH1A1 | |
| SCHEMBL17593181 | 0.82 | KMT2A (0.92) | MEN1KMT2AALDH1A1PKMMAPT | |
| SCHEMBL893905 | 0.82 | CA12 (0.73) | MEN1KMT2APGRITGA1ALDH1A1 | |
| SCHEMBL7584032 | 0.81 | CES1 (0.81) | MEN1KMT2APGRCES1ALDH1A1 | |
| SCHEMBL9310816 | 0.81 | NAMPT (0.71) | MEN1KMT2APGRITGA1CES1 | |
| SCHEMBL3468159 | 0.81 | PGR (0.68) | MEN1KMT2APGRITGA1BRD4 | |
| SCHEMBL13028457 | 0.80 | WDR5 (0.68) | MEN1KMT2APGRCES1WDR5 | |
| SCHEMBL5801508 | 0.79 | PGR (0.91) | MEN1KMT2APGRCES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432994-A | SUBSTITUTED BENZOPHENONE HYDRAZONES AS INSECTICIDES, MITICIDES | THE BOOTS COMPANY (GB) | 1984-02-21 | — | — | US | disclosed |
| US-4331680-A | SUBSTITUTED BENZOPHENONE HYDRAZONE, INSECTICIDES | THE BOOTS COMPANY (GB) | 1982-05-25 | — | — | US | disclosed |
| EP-0026040-A1 | Substituted benzophenone hydrazones, pesticidal compositions containing them and method of combating pests | FBC LIMITED (GB) | 1981-04-01 | — | — | EP | disclosed |