Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048173 | 0.86 | SLC6A4 (0.46) | SLC6A4OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11045957 | 0.79 | OPRM1 (0.49) | SLC6A4OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL7602755 | 0.78 | AKR1C1 (0.50) | SLC6A4MEN1KMT2AAKR1C1NPSR1 | |
| SCHEMBL5129613 | 0.74 | AKR1C1 (0.47) | SLC6A4MEN1KMT2AAKR1C1NPSR1 | |
| SCHEMBL4639359 | 0.73 | AKR1C1 (0.56) | OPRM1OPRL1MEN1KMT2AAKR1C1 | |
| SCHEMBL20242106 | 0.73 | SLC6A4 (0.54) | SLC6A4OPRM1MEN1KMT2AAKR1C1 | |
| SCHEMBL11444396 | 0.72 | MEN1 (0.62) | SLC6A4MEN1KMT2AAKR1C1NPSR1 | |
| SCHEMBL19469690 | 0.72 | ELOVL1 (0.47) | SLC6A4MEN1KMT2AAKR1C1NPSR1 | |
| SCHEMBL31687568 | 0.70 | MAPT (0.42) | SLC6A4MEN1KMT2APOLBNPC1 | |
| SCHEMBL4639100 | 0.70 | AKR1C1 (0.63) | MEN1KMT2AAKR1C1NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478836-A | 1-Aryl 2-aminomethyl cyclopropane carboxyamide (Z) derivatives and their use as useful drugs in the treatment of disturbances of the central nervous system | PIERRE FABRE S.A. (FR) | 1984-10-23 | — | — | US | disclosed |