Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048801 | 0.93 | SIGMAR1 (0.41) | SIGMAR1GSK3AGSK3BMGLLLMNA | |
| SCHEMBL23036031 | 0.76 | LMNA (0.42) | SIGMAR1GSK3AGSK3BMGLLALDH1A1 | |
| SCHEMBL8804597 | 0.73 | SIGMAR1 (0.39) | SIGMAR1GSK3AGSK3BMGLLALDH1A1 | |
| SCHEMBL5969762 | 0.71 | ADRA1D (0.38) | ALDH1A1GAA | |
| SCHEMBL25379874 | 0.70 | LMNA (0.41) | SIGMAR1GSK3AGSK3BMGLLALDH1A1 | |
| SCHEMBL5174444 | 0.70 | SIGMAR1 (0.36) | SIGMAR1GSK3AGSK3BMGLLALDH1A1 | |
| Bromide SCHEMBL29099282 | 0.69 | SIGMAR1 (0.38) | SIGMAR1GSK3AGSK3BMGLLALDH1A1 | |
| SCHEMBL28790693 | 0.69 | ALDH1A1 (0.41) | SIGMAR1L3MBTL1ALDH1A1LMNANPSR1 | |
| Bromide SCHEMBL28711468 | 0.68 | SIGMAR1 (0.37) | SIGMAR1GSK3AGSK3BMGLLL3MBTL1 | |
| SCHEMBL9817613 | 0.67 | CYP2D6 (0.38) | SIGMAR1NPSR1LOXL2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624110-A | Inhibitor of lysyloxidase sample 2 and application thereof | 法玛克亚公司 | 2018-01-23 | — | — | CN | disclosed |