Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915678 | 1.00 | ACHE (0.39) | ACHEMAOAGRM5S1PR1DRD2 | |
| Bromide SCHEMBL9480751 | 0.98 | DRD2 (0.40) | ACHEMAOAGRM5S1PR1DRD2 | |
| SCHEMBL1884804 | 0.94 | S1PR1 (0.41) | ACHEMAOAS1PR1 | |
| SCHEMBL29915622 | 0.90 | MEN1 (0.42) | ACHEMAOADRD2DRD1DRD4 | |
| SCHEMBL111871 | 0.90 | MEN1 (0.42) | ACHEMAOADRD2DRD1DRD4 | |
| SCHEMBL28673277 | 0.86 | MEN1 (0.44) | ACHEMEN1ALDH1A1KMT2A | |
| SCHEMBL107921 | 0.82 | NOTUM (0.40) | ACHEMAOADRD2DRD1DRD4 | |
| SCHEMBL29803467 | 0.82 | NOTUM (0.40) | ACHEMAOADRD2DRD1DRD4 | |
| SCHEMBL14235439 | 0.81 | MEN1 (0.40) | MAOADRD2DRD1DRD4DRD5 | |
| Bromide SCHEMBL9480957 | 0.81 | DRD2 (0.40) | ACHEMAOADRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018445-A1 | OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2021-02-04 | — | — | WO | claimed |
| EP-2582351-B1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| EP-2037871-B1 | OXIDATION DYES FOR DYEING KERATIN FIBERS CONTAINING ATMOSPHERIC OXYGEN AS THE ONLY OXIDIZING AGENT | HENKEL AG & CO KGAA (DE) | 2016-02-24 | — | — | EP | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| US-8734530-B2 | Colorants in foam form | HENKEL AG & CO. KGAA (DE) | 2014-05-27 | — | — | US | claimed |
| US-8597373-B2 | Hair dyeing process using a composition comprising at least one indole or indoline compound, a metal salt, hydrogen peroxide and a basifying agent | L'OREAL (FR) | 2013-12-03 | — | — | US | claimed |
| US-20130174864-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'OREAL (FR) | 2013-07-11 | — | — | US | claimed |
| EP-2606935-A2 | Air oxidative hair dye for glossy dyeings | Henkel AG&Co. KGAA (DE) | 2013-06-26 | — | — | EP | claimed |
| US-20130125917-A1 | COLORANTS IN FOAM FORM | HENKEL AG & CO. KGAA (DE) | 2013-05-23 | — | — | US | claimed |
| WO-2001093818-A1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-13 | — | — | WO | claimed |
| WO-2001093819-A1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-13 | — | — | WO | claimed |
| CN-1047592-C | Tinctorial composition of 5,6-dihydroxyindole and dyeing method of keratose fibre | OREAL (FR) | 1999-12-22 | — | — | CN | claimed |
| EP-0462857-B2 | Dyeing composition containing 5-6 dihydroxyindolines and keratinous fibres dyeing process | OREAL (FR) | 1998-03-04 | — | — | EP | claimed |
| US-5690697-A | COMPOSITION OF AN INDOLE OR INDOLINE COMPOUND, A MANGANESE SALT, A BASIFYING AGENT AND AN OXIDIZER | L'OREAL (FR) | 1997-11-25 | — | — | US | claimed |
| EP-0697209-B1 | Set, process, device and keratineous fibres dyeing composition | OREAL (FR) | 1996-10-09 | — | — | EP | claimed |
| EP-0697210-B1 | Use of a manganese, zinc and/or cobalt salt in a two-steps dyeing process based on an ondole or indoline compound | OREAL (FR) | 1996-09-25 | — | — | EP | claimed |
| US-5538517-A | NONDESTRUCTIVE HAIR DYES | L'OREAL (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0645999-B1 | METHOD FOR DYEING KERATIN FIBRES WITH INDOLE OR INDOLIN DERIVATIVES, HYDROGEN PEROXIDE AND A PEROXIDASE | OREAL (FR) | 1996-01-31 | — | — | EP | claimed |
| US-5178637-A | Hair dyes | L'OREAL (FR) | 1993-01-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130125917-A1 | COLORANTS IN FOAM FORM | KRT18, FH, FLNA | ACHE 1098/4885MAOA 217/4885GRM5 3845/4885 |
| US-20130174864-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | KRT18, HCN4, IDO1 | ACHE 512/4885MAOA 18/4885GRM5 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.