SCHEMBL1884804

SCHEMBL1884804

CCCCCCN1CCc2cc(O)c(O)cc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ S1PR1 P21453 1/20 0.41
▸ ACHE P22303 2/20 0.40
▸ ABCB1 P08183 1/20 0.38
▸ SOAT1 P35610 1/20 0.38
▸ MAOA P21397 1/20 0.37
▸ ALOX5 P09917 1/20 0.36
▸ EPHX2 P34913 1/20 0.36
▸ HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110491 0.94 ACHE (0.39) S1PR1ACHEMAOA
SCHEMBL29915678 0.94 ACHE (0.39) S1PR1ACHEMAOA
Bromide SCHEMBL9480751 0.92 DRD2 (0.40) S1PR1ACHEMAOA
SCHEMBL28673277 0.89 MEN1 (0.44) ACHEABCB1ALOX5HTT
SCHEMBL111871 0.87 MEN1 (0.42) ACHEMAOAHTT
SCHEMBL29915622 0.87 MEN1 (0.42) ACHEMAOAHTT
SCHEMBL16494325 0.82 S1PR1 (0.48) S1PR1ACHEALOX5EPHX2
SCHEMBL29803467 0.80 NOTUM (0.40) ACHEMAOA
SCHEMBL107921 0.80 NOTUM (0.40) ACHEMAOA
Bromide SCHEMBL9480957 0.78 DRD2 (0.40) ACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 — — EP claimed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 — — US claimed
EP-2708223-B1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2017-02-01 — — EP disclosed
EP-3067041-A1 METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE Shisei Chemical Co., Ltd. (JP) 2016-09-14 — — EP disclosed
US-9358198-B2 Dyeing of keratin fibers using indole analogue AMANO ENZYME INC. (JP) 2016-06-07 — — US disclosed
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 — — EP disclosed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 — — US disclosed
US-8740994-B2 Dyeing agent and use for same AMANO ENZYME INC. (JP) 2014-06-03 — — US disclosed
EP-2708223-A1 DYEING AGENT AND USE FOR SAME Amano Enzyme Inc. (JP) 2014-03-19 — — EP disclosed
US-20140068875-A1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2014-03-13 — — US disclosed
EP-2623093-A1 DYE FOR KERATIN FIBERS USING INDOLE ANALOGUE Amano Enzyme Inc. (JP) 2013-08-07 — — EP disclosed
US-6958080-B2 Compositions for dyeing keratinous fiber LION CORPORATION (JP) 2005-10-25 — — US disclosed
US-20050170485-A1 Culture having phenol oxidase-like activity MANDOM CORPORATION (JP) 2005-08-04 — — US disclosed
EP-1533371-A1 CULTURE HAVING PHENOL OXIDASE-LIKE ACTIVITY Mandom Corporation (JP) 2005-05-25 — — EP disclosed
US-20030106166-A1 Compositions for dyeing keratinous fiber LION CORPORATION (JP) 2003-06-12 — — US disclosed
US-20030074743-A1 Hair dye composition LION CORPORATION (JP) 2003-04-24 — — US disclosed
EP-1240890-A1 HAIR DYE COMPOSITION Lion Corporation (JP) 2002-09-18 — — EP disclosed
EP-1234569-A1 COMPOSITIONS FOR DYEING HORNY FIBERS Lion Corporation (JP) 2002-08-28 — — EP disclosed
EP-1142561-A1 HAIR DYE COMPOSITIONS Lion Corporation (JP) 2001-10-10 — — EP disclosed
EP-1142562-A1 HAIR DYE COMPOSITIONS Lion Corporation (JP) 2001-10-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030106166-A1 Compositions for dyeing keratinous fiber KRT18, LPO, CKMT1A; CKMT1B S1PR1 4846/4885ACHE 485/4885ABCB1 4460/4885
US-20030074743-A1 Hair dye composition HAAO, GRHPR, CD44 S1PR1 2960/4885ACHE 757/4885ABCB1 2904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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