Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11190139 | 0.84 | LMNA (0.38) | OPRM1LMNADNM1TSHRPSMD14 | |
| Hydrochloric Acid SCHEMBL5849103 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL31374472 | 0.79 | DNM1 (0.39) | OPRM1LMNADNM1TSHRSMN1; SMN2 | |
| Water SCHEMBL7549052 | 0.79 | TSHR (0.33) | TSHR | |
| Bromide SCHEMBL28243684 | 0.77 | ALDH1A1 (0.48) | DNM1TSHRSMN1; SMN2HSP90AA1SLC22A1 | |
| SCHEMBL27650549 | 0.75 | OPRM1 (0.40) | OPRM1LMNADNM1TSHRFDPS | |
| SCHEMBL22442304 | 0.75 | OPRM1 (0.40) | OPRM1LMNADNM1TSHRPSMD14 | |
| SCHEMBL2339806 | 0.73 | LMNA (0.41) | OPRM1LMNADNM1TSHRSLC22A1 | |
| SCHEMBL8327147 | 0.73 | LMNA (0.41) | OPRM1LMNADNM1TSHRSLC22A1 | |
| Bromide SCHEMBL22442300 | 0.73 | DNM1 (0.39) | OPRM1LMNADNM1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037580-B1 | PROCESS FOR THE SELECTIVE HOMOLOGATION OF METHANOL TO ETHANOL | UNION CARBIDE CORPORATION (US) | 1984-09-19 | — | — | EP | disclosed |
| EP-0037586-B1 | PROCESS FOR THE SELECTIVE HYDROFORMYLATION OF METHANOL TO ACETALDEHYDE | UNION CARBIDE CORPORATION (US) | 1984-03-14 | — | — | EP | disclosed |
| US-4337365-A | COBALT AND IODIDE CATALYST, HIGH TEMPERATURE, INERT ETHER SOLVENT | UNION CARBIDE CORPORATION (US) | 1982-06-29 | — | — | US | disclosed |
| EP-0037586-A1 | Process for the selective hydroformylation of methanol to acetaldehyde | UNION CARBIDE CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0037580-A1 | Process for the selective homologation of methanol to ethanol | UNION CARBIDE CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| US-4277634-A | SYNERGISTIC COMBINATION OF COBALT CATALYST, IODINE PROMOTER, AND INERT SOLVENT | UNION CARBIDE CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |