Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21026389 | 0.80 | CA2 (0.39) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL11820221 | 0.78 | NPC1 (0.44) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL28109463 | 0.78 | MEN1 (0.62) | NPC1MEN1MAPTKMT2ARAB9A | |
| SCHEMBL11408434 | 0.78 | RAPGEF4 (0.55) | NPC1MEN1MAPTKMT2AGAA | |
| SCHEMBL12614443 | 0.78 | RAPGEF4 (0.59) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL11611979 | 0.76 | EPHX1 (0.54) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL856883 | 0.74 | EPHX1 (0.52) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL29502263 | 0.74 | MAPT (0.55) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL19828138 | 0.74 | EPHX1 (0.52) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL30667273 | 0.74 | EPHX1 (0.52) | EPHX1EPHX2CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727462-B1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BICYCLERD LTD (GB) | 2025-11-05 | — | — | EP | claimed |
| US-11623012-B2 | Bicyclic peptide ligands specific for EphA2 | Bicyclerd Limited (GB) | 2023-04-11 | — | — | US | claimed |
| EP-0119892-B1 | HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF | ROUSSEL-UCLAF (FR) | 1986-08-13 | — | — | EP | claimed |
| US-20260124312-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BICYCLETX LIMITED (GB) | 2026-05-07 | — | — | US | disclosed |
| EP-3727462-B1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BICYCLERD LTD (GB) | 2025-11-05 | — | — | EP | disclosed |
| US-20250255975-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP | Bicyclerd Limited (GB) | 2025-08-14 | — | — | US | disclosed |
| EP-4582436-A2 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BicycleTX Limited (GB) | 2025-07-09 | — | — | EP | disclosed |
| EP-3727461-B1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | BICYCLETX LTD (GB) | 2025-07-09 | — | — | EP | disclosed |
| US-12318454-B2 | Bicyclic peptide ligands specific for MT1-MMP | Bicyclerd Limited (GB) | 2025-06-03 | — | — | US | disclosed |
| US-20240082410-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP | Bicyclerd Limited (GB) | 2024-03-14 | — | — | US | disclosed |
| US-20240000957-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 | BICYCLETX LIMITED (GB) | 2024-01-04 | — | — | US | disclosed |
| CN-104961747-A | Tetrahydrobenzo [ d ] [1,2,6] oxadinitrogen compound and preparation method thereof | UNIV DALIAN TECH | 2015-10-07 | — | — | CN | disclosed |
| EP-0119892-B1 | HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF | ROUSSEL-UCLAF (FR) | 1986-08-13 | — | — | EP | disclosed |
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-3992395-A | Process for the preparation of chlorinated phenylhydroxylamines | RHONE-POULENC S.A. (FR) | 1976-11-16 | — | — | US | disclosed |
| US-3982922-A | Herbicidal compositions containing furancarboxamides | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
| US-3944410-A | Substituted oxadiazolidine dione herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11623012-B2 | Bicyclic peptide ligands specific for EphA2 | EPHA2, EPHB2, EPHB3 | EPHX1 147/4885EPHX2 22/4885CA2 3092/4885 |
| US-20250255975-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP | MMEL1, MMP3, TIMP3 | EPHX1 3678/4885EPHX2 3396/4885CA2 1489/4885 |
| US-20240000957-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EphA2 | EPHA2, EPHB2, ERBB2 | EPHX1 109/4885EPHX2 21/4885CA2 3156/4885 |
| US-20260124312-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 | EPHA2, EPHB2, ERBB2 | EPHX1 313/4885EPHX2 79/4885CA2 2442/4885 |
| US-12318454-B2 | Bicyclic peptide ligands specific for MT1-MMP | MMEL1, MMP3, TIMP3 | EPHX1 3678/4885EPHX2 3396/4885CA2 1489/4885 |
| US-20240082410-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP | MMEL1, MMP3, TIMP3 | EPHX1 3678/4885EPHX2 3396/4885CA2 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.