Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337425 | 0.92 | CA2 (0.39) | CA1CA2ESR1ESR2PTGS1 | |
| SCHEMBL24190794 | 0.86 | GAA (0.50) | CA1CA2ESR1ESR2PTGS1 | |
| SCHEMBL30429057 | 0.86 | GAA (0.50) | CA1CA2ESR1ESR2PTGS1 | |
| SCHEMBL11433564 | 0.84 | CA1 (0.44) | CA1CA2ESR1ESR2PTGS1 | |
| SCHEMBL24332735 | 0.83 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL22326117 | 0.79 | ALDH1A1 (0.44) | ESR1ESR2ALDH1A1GAAMAPT | |
| SCHEMBL27272407 | 0.79 | GLA (0.37) | ESR1ESR2CYP1A2CYP2C9MAPT | |
| SCHEMBL24191114 | 0.78 | GPR35 (0.56) | CA1CA2PTGS2CYP1A2CYP2C9 | |
| SCHEMBL30429503 | 0.78 | GPR35 (0.56) | CA1CA2PTGS2CYP1A2CYP2C9 | |
| SCHEMBL11050693 | 0.76 | ESR1 (0.50) | ESR1ESR2PTGS1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365098-A | Fluorinated diphenols and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 1982-12-21 | — | — | US | claimed |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2025-10-07 | — | — | US | disclosed |
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2022-04-07 | — | — | US | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
| US-4467121-A | Fluorinated diphenols and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4379910-A | Flame retardant aromatic polycarbonate compositions made from fluorinated diphenols | GENERAL ELECTRIC CO. (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0067853-A4 | FLAME RETARDANT AROMATIC POLYCARBONATES MADE FROM FLUORINATED DIPHENOLS. | GEN ELECTRIC (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0067853-A1 | FLAME RETARDANT AROMATIC POLYCARBONATES MADE FROM FLUORINATED DIPHENOLS. | GEN ELECTRIC (US) | 1982-12-29 | — | — | EP | disclosed |
| WO-1982002402-A1 | FLAME RETARDANT AROMATIC POLYCARBONATE COMPOSITIONS MADE FROM FLUORINATED DIPHENOLS | GEN ELECTRIC (US) | 1982-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | NAF1, FXR1, AFF1 | CA1 337/4885CA2 424/4885ESR1 4737/4885 |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | NAF1, FXR1, AFF1 | CA1 337/4885CA2 424/4885ESR1 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.