Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.41 |
| ▸ | CBLB | Q13191 | 5/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7100993 | 0.86 | ZDHHC20 (0.46) | KMT2AATMCBLBZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL22687484 | 0.85 | APEX1 (0.40) | KMT2AATMCBLBAPEX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL233973 | 0.84 | APEX1 (0.41) | KMT2AATMBBOX1CBLBAPEX1 | |
| SCHEMBL4659384 | 0.84 | ZDHHC20 (0.47) | CBLBZDHHC20ZDHHC2DNM1HTT | |
| SCHEMBL1628096 | 0.82 | APEX1 (0.42) | KMT2AATMBBOX1CBLBAPEX1 | |
| SCHEMBL25544701 | 0.82 | APEX1 (0.42) | KMT2AATMBBOX1CBLBAPEX1 | |
| Hydrochloric Acid SCHEMBL562283 | 0.81 | ZDHHC20 (0.56) | KMT2AATMBBOX1CBLBALDH1A1 | |
| SCHEMBL25187770 | 0.80 | CBLB (0.43) | KMT2AATMBBOX1CBLBAPEX1 | |
| SCHEMBL475893 | 0.79 | ZDHHC20 (0.58) | KMT2AATMBBOX1CBLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL10456825 | 0.79 | LMNA (0.45) | KMT2AATMCBLBAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454060-A | Liquid detergent composition with a cationic foam stabilizing copolymer containing pendant quaternary nitrogen groups and pendant hydrophobic groups | COLGATE-PALMOLIVE COMPANY (US) | 1984-06-12 | — | — | US | disclosed |