Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CBLB | Q13191 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659384 | 0.98 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2HTTDNM1EGFR | |
| Hydrochloric Acid SCHEMBL11054825 | 0.86 | KMT2A (0.42) | ZDHHC20ZDHHC2HTTDNM1EGFR | |
| SCHEMBL21731701 | 0.84 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2EGFREPHX1 | |
| SCHEMBL19363595 | 0.84 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2EGFREPHX1 | |
| SCHEMBL8511129 | 0.84 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2EGFREPHX1 | |
| Hydrochloric Acid SCHEMBL2489185 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1CBLB | |
| Hydrochloric Acid SCHEMBL11232338 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1CBLB | |
| Hydrochloric Acid SCHEMBL3046560 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1CBLB | |
| Hydrochloric Acid SCHEMBL28572838 | 0.83 | ZDHHC20 (0.70) | ZDHHC20ZDHHC2HTTDNM1CBLB | |
| SCHEMBL7532607 | 0.82 | ZDHHC20 (0.60) | ZDHHC20ZDHHC2HTTEGFREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10456349-B2 | Product for keratin fibers, containing at least one copolymer based on vinylpyrrolidone and at least one copolymer based on acrylates | HENKEL AG & CO. KGAA (DE) | 2019-10-29 | — | — | US | disclosed |
| US-20180064627-A1 | PRODUCT FOR KERATIN FIBERS, CONTAINING AT LEAST ONE COPOLYMER BASED ON VINYLPYRROLIDONE AND AT LEAST ONE COPOLYMER BASED ON ACRYLATES | HENKEL AG & CO. KGAA (DE) | 2018-03-08 | — | — | US | disclosed |
| EP-0859547-B1 | VIRUS INACTIVATING COATINGS | SURMODICS INC (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0859547-A4 | VIRUS INACTIVATING COATINGS | SURMODICS INC (US) | 2000-12-20 | — | — | EP | disclosed |
| EP-0859547-A1 | VIRUS INACTIVATING COATINGS | BSI Corporation (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1996039821-A1 | VIRUS INACTIVATING COATINGS | BSI CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064627-A1 | PRODUCT FOR KERATIN FIBERS, CONTAINING AT LEAST ONE COPOLYMER BASED ON VINYLPYRROLIDONE AND AT LEAST ONE COPOLYMER BASED ON ACRYLATES | KRT18, CUTA, ACR | ZDHHC20 2057/4885ZDHHC2 2946/4885HTT 1529/4885 |
| US-10456349-B2 | Product for keratin fibers, containing at least one copolymer based on vinylpyrrolidone and at least one copolymer based on acrylates | KRT18, CUTA, ACR | ZDHHC20 2022/4885ZDHHC2 2858/4885HTT 1576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.