Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060675 | 0.93 | LMNA (0.33) | MAP3K7TAB1MAPTHSD17B10PRKD3 | |
| SCHEMBL11058190 | 0.89 | PARP10 (0.32) | — | |
| SCHEMBL11058669 | 0.82 | GPBAR1 (0.33) | — | |
| SCHEMBL11064906 | 0.80 | MAP3K7 (0.32) | MAP3K7TAB1MAPTHSD17B10PRKD3 | |
| SCHEMBL11058625 | 0.79 | MAP3K7 (0.36) | MAP3K7TAB1 | |
| SCHEMBL11060945 | 0.77 | RPS6KB1 (0.30) | — | |
| SCHEMBL11062439 | 0.76 | GABRP (0.35) | MAPT | |
| SCHEMBL11058664 | 0.74 | — | — | |
| SCHEMBL11061057 | 0.72 | MAP3K7 (0.37) | MAP3K7TAB1MAPTHSD17B10PRKD3 | |
| SCHEMBL11058684 | 0.70 | LMNA (0.43) | MAP3K7TAB1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |