Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058765 | 0.87 | ADORA3 (0.34) | GAAMAPTALDH1A1LMNA | |
| SCHEMBL11066089 | 0.79 | MAPT (0.36) | GAAMAPTALDH1A1LMNA | |
| SCHEMBL11062388 | 0.77 | — | — | |
| SCHEMBL10959912 | 0.74 | MAPT (0.36) | GAAMAPTALDH1A1LMNA | |
| SCHEMBL11062612 | 0.74 | HTT (0.35) | GAAMAPTALDH1A1 | |
| SCHEMBL10957823 | 0.74 | ALDH1A1 (0.37) | GAAMAPTALDH1A1LMNA | |
| SCHEMBL11058744 | 0.72 | MEN1 (0.33) | MAPTALDH1A1LMNA | |
| SCHEMBL10956420 | 0.71 | MAPT (0.36) | GAAMAPTALDH1A1 | |
| SCHEMBL11055958 | 0.70 | HTT (0.40) | MAPTALDH1A1 | |
| SCHEMBL11061474 | 0.70 | L3MBTL1 (0.34) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |