Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059523 | 0.76 | ALDH1A1 (0.34) | KMT2ATSHRALDH1A1HTT | |
| SCHEMBL11058765 | 0.76 | ADORA3 (0.34) | MEN1KMT2ACYP1A2ALDH1A1HTT | |
| SCHEMBL11060997 | 0.73 | MEN1 (0.36) | MEN1KMT2ACYP1A2ALDH1A1LMNA | |
| SCHEMBL10959912 | 0.72 | MAPT (0.36) | MEN1KMT2AALDH1A1HTTLMNA | |
| SCHEMBL11058255 | 0.72 | GAA (0.31) | ALDH1A1LMNAMAPT | |
| SCHEMBL11062426 | 0.69 | MAPT (0.34) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL11062101 | 0.69 | HTT (0.33) | KMT2AHTT | |
| SCHEMBL11062622 | 0.68 | CDK1 (0.33) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL11066089 | 0.68 | MAPT (0.36) | ALDH1A1HTTLMNAMAPTL3MBTL1 | |
| SCHEMBL11061474 | 0.68 | L3MBTL1 (0.34) | MEN1KMT2ACYP1A2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |