Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959341 | 0.84 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4MAPTGLA | |
| SCHEMBL11064903 | 0.82 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4MAPTGLA | |
| SCHEMBL11061474 | 0.79 | L3MBTL1 (0.34) | L3MBTL1CYP1A2CYP3A4MAPTGLA | |
| SCHEMBL11065739 | 0.76 | ALDH1A1 (0.33) | L3MBTL1CYP1A2CYP3A4GLAALDH1A1 | |
| SCHEMBL16693782 | 0.75 | LMNA (0.34) | NTRK1ALDH1A1HTTLMNAMEN1 | |
| SCHEMBL11058666 | 0.75 | ATR (0.37) | L3MBTL1CYP1A2CYP3A4MAPTGLA | |
| SCHEMBL26789781 | 0.75 | HTT (0.43) | MAPTNTRK1ALDH1A1HTTNPSR1 | |
| SCHEMBL10957823 | 0.74 | ALDH1A1 (0.37) | L3MBTL1CYP1A2MAPTALDH1A1HTT | |
| SCHEMBL11065100 | 0.74 | MEN1 (0.35) | L3MBTL1MEN1KMT2A | |
| SCHEMBL19782405 | 0.71 | NNMT (0.51) | L3MBTL1CYP1A2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |