Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MPEG1 | Q2M385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065726 | 0.90 | XDH (0.37) | MEN1KMT2AXDH | |
| SCHEMBL11061474 | 0.78 | L3MBTL1 (0.34) | MEN1PABPC1KMT2AL3MBTL1 | |
| SCHEMBL11060716 | 0.76 | MEN1 (0.36) | MEN1PABPC1KMT2AXDH | |
| SCHEMBL11058685 | 0.74 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL10959341 | 0.74 | L3MBTL1 (0.37) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL11065739 | 0.72 | ALDH1A1 (0.33) | L3MBTL1 | |
| SCHEMBL11062622 | 0.72 | CDK1 (0.33) | MEN1KMT2AXDH | |
| SCHEMBL11062388 | 0.71 | — | — | |
| SCHEMBL11065105 | 0.71 | MEN1 (0.31) | MEN1KMT2AALOX5 | |
| SCHEMBL11060997 | 0.69 | MEN1 (0.36) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |