Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959341 | 0.79 | L3MBTL1 (0.37) | ALDH1A1L3MBTL1CYP1A2CYP3A4GLA | |
| SCHEMBL11061474 | 0.77 | L3MBTL1 (0.34) | L3MBTL1CYP1A2CYP3A4GLA | |
| SCHEMBL11058685 | 0.76 | L3MBTL1 (0.40) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11065100 | 0.72 | MEN1 (0.35) | L3MBTL1 | |
| SCHEMBL11060716 | 0.70 | MEN1 (0.36) | LMNACYP3A4 | |
| SCHEMBL11058666 | 0.68 | ATR (0.37) | L3MBTL1CYP1A2CYP3A4GLA | |
| SCHEMBL11060997 | 0.68 | MEN1 (0.36) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL11064903 | 0.66 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4GLA | |
| SCHEMBL11058186 | 0.63 | ALDH1A1 (0.33) | ALDH1A1LMNAL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL21376744 | 0.63 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |