Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053513 | 0.91 | MAPK14 (0.39) | CHRNA7MAPK14P2RX7FABP3FABP4 | |
| SCHEMBL11055027 | 0.90 | CHRNA7 (0.44) | CHRNA7MAPK14P2RX7KDM4EALDH1A1 | |
| SCHEMBL11056305 | 0.90 | MEN1 (0.38) | CHRNA7MAPK14P2RX7 | |
| SCHEMBL11057683 | 0.88 | MAPK14 (0.34) | CHRNA7MAPK14P2RX7 | |
| SCHEMBL11055462 | 0.85 | HCAR2 (0.35) | MAPK14ALDH1A1HPGD | |
| SCHEMBL11055569 | 0.80 | CHRNA7 (0.43) | CHRNA7LCK | |
| SCHEMBL11059411 | 0.80 | KMT2A (0.36) | CHRNA7ALDH1A1 | |
| SCHEMBL11052478 | 0.78 | TDP2 (0.33) | CHRNA7MAPK14P2RX7ALDH1A1HPGD | |
| SCHEMBL11060185 | 0.74 | ALDH1A1 (0.33) | MAPK14ALDH1A1HPGD | |
| SCHEMBL11059482 | 0.74 | HCAR2 (0.37) | P2RX7ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452980-A | DIARRHEA | WILLIAM H. RORER, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4246409-A | ANTIDIARRHEAL AGENTS | WILLIAM H. RORER, INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4225315-A | Triazinones from amidinoureas | WILLIAM H. RORER, INC. (US) | 1980-09-30 | — | — | US | disclosed |