SCHEMBL479304

SCHEMBL479304

Nc1ccc(S(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
LMNA P02545 4/20 0.54
TSHR P16473 3/20 0.54
HTR6 P50406 2/20 0.54
MPO P05164 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
CA2 P00918 7/20 0.52
CA1 P00915 6/20 0.52
CA12 O43570 6/20 0.52
CA9 Q16790 6/20 0.52
CA14 Q9ULX7 2/20 0.52
AGO2 Q9UKV8 2/20 0.52
USP2 O75604 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3910315 0.94 CA12 (0.57) ALDH1A1LMNATSHRHTR6MPO
SCHEMBL11060588 0.88 PTPRZ1 (0.53) ALDH1A1LMNATSHRHTR6MPO
SCHEMBL4800836 0.88 KIF11 (0.53) ALDH1A1LMNATSHRHTR6MPO
SCHEMBL11221276 0.82 CA2 (0.50) ALDH1A1LMNATSHRHTR6MPO
SCHEMBL11232528 0.82 CA2 (0.50) ALDH1A1LMNATSHRHTR6MPO
SCHEMBL6849852 0.81 CA2 (0.57) ALDH1A1LMNATSHRCA2CA1
SCHEMBL7937243 0.78 ALDH1A1 (0.52) ALDH1A1LMNACA2CA1MAPK1
SCHEMBL517720 0.78 ALDH1A1 (0.52) ALDH1A1LMNACA2MAPK1HTT
SCHEMBL14310620 0.77 F2 (0.63) ALDH1A1LMNATSHRHTR6CA2
SCHEMBL1098295 0.76 GAA (0.54) ALDH1A1LMNACYP3A4CYP2C9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702949-A Perovskite quantum dot-polymer composite film and preparation method thereof 中国矿业大学 2022-07-05 CN claimed
US-20100041657-A1 HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES NOVO NORDICK A/S (DK) 2010-02-18 US claimed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP claimed
EP-1881961-A1 NEW HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES NOVO NORDISK A/S (DK) 2008-01-30 EP claimed
JP-2007523865-A 2007-08-23 JP claimed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP claimed
WO-2006120178-A1 NEW HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES NOVO NORDISK A/S (DK) 2006-11-16 WO claimed
US-7129235-B2 Amides useful for treating pain ABBOTT LABORATORIES (US) 2006-10-31 US claimed
EP-1646621-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN Abbott Laboratories (US) 2006-04-19 EP claimed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO claimed
US-20050080095-A1 administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I ABBVIE INC. 2005-04-14 US claimed
WO-2005007642-A2 NOVEL AZAHETEROCYCLIC AMIDES USEFUL FOR TREATING PAIN ABBOTT LABORATORIES (US) 2005-01-27 WO claimed
WO-2002028353-A2 PHOSPHATE TRANSPORT INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-11 WO claimed
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF LYSOWAY THERAPEUTICS INC (US) 2025-10-30 US disclosed
CN-116023321-B STING inhibitor prodrug and medical application thereof 中国药科大学 2024-11-29 CN disclosed
CN-114702949-B Perovskite quantum dot-polymer composite film and preparation method thereof 中国矿业大学 2024-02-27 CN disclosed
EP-0010249-A2 Herbicidal agents, process for their preparation and their use in combating weeds BAYER AG (DE) 1980-04-30 EP disclosed
EP-0010250-A2 Use of Sulfonanilides in inhibition of plant growth BAYER AG (DE) 1980-04-30 EP disclosed
EP-0008435-A2 Substituted N-phenyl-N'-benzoyl-thioureas, their preparation and their use as pesticides BAYER AG (DE) 1980-03-05 EP disclosed
EP-0000156-A1 2-Arylamino-3,5-dinitro-benzotrifluorides, process for their preparation and their use as pesticides. BAYER AG (DE) 1979-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041657-A1 HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES RPS12, GPR119, ATP12A ALDH1A1 899/4885LMNA 4278/4885TSHR 1003/4885
US-20050080095-A1 administering a therapeuitcally effective amount of 3'-(trifluoromethyl)-N-{4-[(trifluoromethyl)sulfonyl]phenyl}-3,6-dihydro-2H-1,2'-bipyridine-4-carboxamide; antagonists of vanilloid receptor subtype I TRPV1, OPRL1, TRPV6 ALDH1A1 843/4885LMNA 2257/4885TSHR 397/4885
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF STOML2, ATP2A3, ATP2A1 ALDH1A1 3204/4885LMNA 624/4885TSHR 3956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.