Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | EPOR | P19235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071446 | 0.91 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP1 | |
| SCHEMBL11064779 | 0.84 | EPOR (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP1 | |
| SCHEMBL11062094 | 0.81 | KCNH2 (0.38) | ALDH1A1ADAMTS4TRPV3KCNH2P2RX3 | |
| SCHEMBL11065707 | 0.78 | ADAMTS4 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP9 | |
| SCHEMBL11275809 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KCNH2HSD17B14PPARG | |
| SCHEMBL11478773 | 0.77 | ADAMTS4 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP9 | |
| SCHEMBL11391609 | 0.77 | L3MBTL1 (0.36) | ALDH1A1SMN1; SMN2TRPV3KCNH2P2RX3 | |
| SCHEMBL11391608 | 0.77 | L3MBTL1 (0.36) | ALDH1A1SMN1; SMN2TRPV3KCNH2P2RX3 | |
| SCHEMBL11072017 | 0.76 | ADAMTS4 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2MMP9 | |
| SCHEMBL11460618 | 0.76 | ALOX5 (0.40) | LMNACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447613-A | Pyridyl esters and thiolesters of aminoalkanoic acids | ZOECON CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4269981-A | Certain pyridylmethyl esters of formamido-lower-alkanoates and derivatives thereof | ZOECON CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4247701-A | Certain pesticidal substituted amino lower-alkanoates or lower-alkano-thioates containing pyridyl in the ester portion | ZOECON CORPORATION (US) | 1981-01-27 | — | — | US | disclosed |