Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062162 | 0.79 | TRPM8 (0.44) | LMNATSHRNPC1ALOX15MAPK1 | |
| SCHEMBL11071361 | 0.73 | PDE3B (0.45) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL11071318 | 0.72 | MAPT (0.41) | — | |
| SCHEMBL11058886 | 0.71 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL11067771 | 0.70 | PDE3B (0.41) | L3MBTL1PDE3BPDE3AMAOAMAOB | |
| SCHEMBL12090742 | 0.70 | CYP19A1 (0.48) | NPC1MAPK1ALDH1A1CYP19A1CYP11B1 | |
| SCHEMBL11278612 | 0.70 | LMNA (0.46) | LMNANPC1MAOAMAOB | |
| SCHEMBL11071895 | 0.70 | PDE3B (0.40) | LMNAPDE3BPDE3ACYP19A1CYP11B1 | |
| SCHEMBL11065352 | 0.70 | KMT2A (0.41) | TSHRNPC1ALOX15MAPK1HSD17B10 | |
| SCHEMBL11069955 | 0.69 | PDE3B (0.50) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |