SCHEMBL5576296

SCHEMBL5576296

C=CCN(N=O)S(=O)(=O)c1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.42
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
KMT2A Q03164 2/20 0.37
RAB9A P51151 2/20 0.36
HCRTR2 O43614 1/20 0.36
MAPT P10636 1/20 0.36
ESR1 P03372 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
S1PR1 P21453 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.34
HSD11B1 P28845 1/20 0.34
PTPN1 P18031 1/20 0.34
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28185888 0.82 RAB9A (0.48) C5AR1HTR2AHTR2CKMT2ARAB9A
SCHEMBL2722524 0.80 KMT2A (0.47) HTR2AHTR2CKMT2AHCRTR2MAPT
SCHEMBL9321976 0.76 L3MBTL1 (0.43) HTR2AHTR2CKMT2AHCRTR2L3MBTL1
SCHEMBL2732037 0.74 C5AR1 (0.59) C5AR1KMT2AMAPTESR1KEAP1
SCHEMBL11062327 0.73 C5AR1 (0.38) C5AR1HTR2AHTR2CKMT2ARAB9A
SCHEMBL5007810 0.71 HTR2A (0.45) C5AR1HTR2AHTR2CKMT2AHCRTR2
SCHEMBL5576829 0.71 HTR2A (0.47) C5AR1HTR2AHTR2CKMT2AHCRTR2
SCHEMBL1078094 0.70 HSP90AA1 (0.44) C5AR1KMT2ARAB9AMAPTESR1
SCHEMBL707747 0.69 ALDH1A1 (0.49) C5AR1KMT2AMAPTL3MBTL1KEAP1
SCHEMBL701463 0.68 ALDH1A1 (0.55) HTR2AHTR2CHCRTR2MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US claimed
CN-1980885-A Method for producing gaseous diazoalkanes DYNAMIT NOBEL AG (DE) 2007-06-13 CN claimed
US-9249088-B2 Continuous production and reaction of a diazo compound DPX HOLDINGS B.V. (NL) 2016-02-02 US disclosed
EP-2635548-B1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DPX HOLDINGS BV (NL) 2014-12-17 EP disclosed
US-20140100360-A1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) 2014-04-10 US disclosed
US-7902342-B2 Method for producing gaseous diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2011-03-08 US disclosed
US-20070249817-A1 Method for Producing Gaseous Diazoalkanes DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2007-10-25 US disclosed
CN-1980885-A Method for producing gaseous diazoalkanes DYNAMIT NOBEL AG (DE) 2007-06-13 CN disclosed