Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RRM2 | P31350 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060944 | 0.86 | L3MBTL1 (0.35) | L3MBTL1MAPTCYP1A2CYP3A4GLA | |
| SCHEMBL11060673 | 0.79 | MAPK1 (0.35) | ALDH1A1 | |
| SCHEMBL11057358 | 0.75 | MAP3K7 (0.36) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11058186 | 0.74 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11058659 | 0.74 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2MAPTHTT | |
| Thiourea SCHEMBL27806269 | 0.72 | RAB9A (0.34) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7345801 | 0.72 | NPC1 (0.37) | ALDH1A1SMN1; SMN2LMNANPC1NFKB1 | |
| SCHEMBL11058666 | 0.70 | ATR (0.37) | L3MBTL1MAPTCYP1A2CYP3A4GLA | |
| SCHEMBL11062439 | 0.68 | GABRP (0.35) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLMNA | |
| SCHEMBL29958220 | 0.67 | CA1 (0.39) | ALDH1A1L3MBTL1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434167-A | Pyrimidyl thioureas useful for the treatment of hypertension and hyperlipidemia | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-02-28 | — | — | US | disclosed |