Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345038 | 0.88 | HSPA5 (0.36) | NPC1RAB9AALDH1A1HSPA5KMT2A | |
| SCHEMBL7350086 | 0.75 | MALT1 (0.45) | NPC1RAB9AHSPA5LMNAAXL | |
| SCHEMBL7353658 | 0.75 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL11062437 | 0.72 | ALDH1A1 (0.35) | NPC1RAB9ASMN1; SMN2ALDH1A1NFKB1 | |
| SCHEMBL11260129 | 0.71 | HTT (0.47) | NPC1RAB9ASMN1; SMN2HSPA5KDM4E | |
| SCHEMBL7349451 | 0.70 | BCAT2 (0.49) | NPC1RAB9ASMN1; SMN2HSPA5KMT2A | |
| SCHEMBL5579468 | 0.70 | NAAA (0.51) | SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL6906056 | 0.69 | MAPT (0.49) | ALDH1A1KMT2ALMNA | |
| SCHEMBL8747369 | 0.69 | NAAA (0.54) | SMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL6663162 | 0.68 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2HSPA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318975-A | 5-pyrimdineamine derivatives | BERLEX LABORATORIES, INC. (US) | 1994-06-07 | — | — | US | disclosed |