Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071039 | 0.88 | DRD2 (0.53) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL11071104 | 0.86 | MAOA (0.61) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11073435 | 0.83 | HTR7 (0.48) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL11070539 | 0.82 | HTR7 (0.47) | DRD2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11066899 | 0.80 | HTR7 (0.50) | DRD2DRD4DRD3HTR7SIGMAR1 | |
| SCHEMBL10569528 | 0.80 | KCNA5 (0.50) | DRD2DRD4DRD3SIGMAR1MAOA | |
| SCHEMBL10572638 | 0.79 | DRD2 (0.63) | DRD2DRD4DRD3MAOAMAOB | |
| SCHEMBL22022834 | 0.79 | KDM1A (0.69) | — | |
| SCHEMBL11062872 | 0.78 | KDM1A (0.66) | DRD2DRD4DRD3HTR7MAOA | |
| SCHEMBL11066640 | 0.78 | MAOA (0.71) | DRD2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |